Holden Lowe

Hazel Evers, Alicia Spencer, Rita Gayheart, Sally Keffler

Mary

Amy Chen

Matt Miller

Mother Superior Claudia

Mason Harris

Guinness

Ishmael Polk

John Lowe, Dylan, Ambrose White, Edward Mordrake

Harrison Renard

Doris Kearns Goodwin

Luke Ramsey

Detective Jack Samuels

Todd Connors

Bonnie Lipton

Sister Mary Eunice McKee, Misty Day, Shelby Miller, Nora Montgomery, Aileen Wuornos

Leo Morrison

Mama Polk, Cynthia Potter

The Axeman, Massimo Dolcefino

Nurse Bridget

Ma Petite

Spalding, Larry Harvey, Liz Taylor, Stanley, Richard Spencer, William van Henderson, Dr. Elias Cunningham, Dr. Sylvester Mansfield, Nick Pryor

Legless Suzi

Ethel Darling, Madame Delphine LaLaurie, Iris, Ms. Miriam Mead, Agnes Mary Winstead, Thomasin 'The Butcher' White

Mom

Ima 'Barbara' Wiggles

Joan Ramsey

Nurse Miranda

Dr. Alex Lowe, Shelley

Dell Toledo